The LCP (Lipidic Cubic Phase) sandwich set consists of a base glass slide and an optimised cover slip. Our LCP sandwich sets from Marienfeld were developed with the Scripps Research Institute in California, USA and are ideal for:

  • Applications using LCP membrane protein structures.
  • Crystallographic studies of membrane proteins.
  • Membrane protein research.

 

Bottom slide

  • Dimensions: 127.8mm x 85.5mm
  • Thickness: 1mm

The bottom slide is covered with 0.2mm spacer which has 96 recesses (which are 5mm in diameter). The recesses are consistent with the SBS format for robotic handling whilst the spacer has an adhesive surface which the cover slip attaches to.

 

Cover slip

  • Dimensions: 112mm x 77mm
  • Thickness: 0.16mm to 0.19mm

The cover slip has been optimised for bright field, UV and fluorescent microscopy.

 

References 

  • V. Cherezov, D. M. Rosenbaum, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, P. Kuhn, W. I. Weis, B. K. Kobilka and R. C. Stevens (2007) High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 318: 1258-65.
  • V. Cherezov, J. Clogston, M. Z. Papiz, M. Caffrey (2006) Room to Move: Crystallizing Membrane Proteins in Swollen Lipidic Mesophases. Journal of Molecular Biology 357, 1605 – 1618

 

 

For more information on our LCP and FRAP sandwich sets or to place an order, please call 0845 263 8908 or email sales@gandn.com. 

Our FRAP (fluorescent recovery after photo-bleaching) sandwich set consists of a base glass slide and an optimised cover slip. The FRAP sets have also been developed with the Scripps Research Institute in California.

 

Bottom slide

  • Dimensions: 127.8mm x 85.5mm
  • Thickness: 1mm

Covered with 0.06mm spacer which containers 96 recesses of 7mm in diameter. The spacer has an adhesive surface which the hydrophobic cover clip can be attached to. Crystalisation drops are then sealed inside these reaction chambers.

 

Cover Slip

  • Dimensions: 112mm x 77mm
  • Thickness: 0.16mm x 0.19mm

The cover slip has been optimised for bright field, UV and fluorescent microscopy.

 


Product  Item Number 
LCP Sandwich Set  701014 
FRAP Sandwich Set  701015

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